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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCYL3
All Species:
9.09
Human Site:
S624
Identified Species:
16.67
UniProt:
Q8IZE3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZE3
NP_065156.5
742
82857
S624
S
S
L
P
Q
K
I
S
L
V
Q
R
G
D
D
Chimpanzee
Pan troglodytes
XP_513987
742
82925
S624
S
S
L
P
Q
K
T
S
L
V
Q
R
G
D
D
Rhesus Macaque
Macaca mulatta
XP_001096051
736
82375
D624
S
S
L
P
Q
N
G
D
D
P
D
Q
I
K
P
Dog
Lupus familis
XP_537198
743
82483
N624
S
S
P
P
Q
K
T
N
H
A
Q
S
R
D
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBQ7
735
81315
H623
S
P
S
S
K
T
S
H
R
Q
H
E
E
V
K
Rat
Rattus norvegicus
Q5M9F8
807
89107
Q671
D
D
W
S
T
K
G
Q
G
N
R
A
G
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514536
1518
163635
F1281
K
I
R
G
L
K
V
F
R
L
D
G
Q
S
S
Chicken
Gallus gallus
NP_001012613
698
77220
G603
S
S
L
E
S
G
L
G
E
E
F
T
I
K
V
Frog
Xenopus laevis
Q561M0
827
91284
A719
P
P
A
K
K
P
T
A
S
K
S
Q
Q
P
E
Zebra Danio
Brachydanio rerio
NP_955951
768
85305
T643
N
H
T
S
S
W
D
T
G
W
N
Q
E
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610175
683
77833
T590
V
N
E
T
I
S
Q
T
E
Q
K
V
I
D
D
Honey Bee
Apis mellifera
XP_001123124
613
70111
N521
S
N
D
I
S
I
P
N
S
T
L
K
I
T
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177952
810
89574
T675
M
V
P
P
K
K
E
T
P
V
P
K
T
A
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.1
85.5
N.A.
80.7
21.9
N.A.
31.8
61.9
21.8
51.9
N.A.
25.7
28.4
N.A.
33.5
Protein Similarity:
100
99.1
96.7
90.3
N.A.
87.7
38.5
N.A.
37.4
71.5
39
67.5
N.A.
45.9
49.7
N.A.
50.7
P-Site Identity:
100
93.3
33.3
46.6
N.A.
6.6
13.3
N.A.
6.6
20
0
0
N.A.
13.3
6.6
N.A.
20
P-Site Similarity:
100
93.3
40
60
N.A.
13.3
20
N.A.
20
26.6
26.6
26.6
N.A.
33.3
26.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
8
0
8
0
8
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
0
0
0
8
8
8
0
16
0
0
31
24
% D
% Glu:
0
0
8
8
0
0
8
0
16
8
0
8
16
0
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
8
0
8
16
8
16
0
0
8
24
0
0
% G
% His:
0
8
0
0
0
0
0
8
8
0
8
0
0
0
0
% H
% Ile:
0
8
0
8
8
8
8
0
0
0
0
0
31
0
0
% I
% Lys:
8
0
0
8
24
47
0
0
0
8
8
16
0
16
8
% K
% Leu:
0
0
31
0
8
0
8
0
16
8
8
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
16
0
0
0
8
0
16
0
8
8
0
0
0
24
% N
% Pro:
8
16
16
39
0
8
8
0
8
8
8
0
0
8
8
% P
% Gln:
0
0
0
0
31
0
8
8
0
16
24
24
16
8
0
% Q
% Arg:
0
0
8
0
0
0
0
0
16
0
8
16
8
0
0
% R
% Ser:
54
39
8
24
24
8
8
16
16
0
8
8
0
8
8
% S
% Thr:
0
0
8
8
8
8
24
24
0
8
0
8
8
8
8
% T
% Val:
8
8
0
0
0
0
8
0
0
24
0
8
0
8
16
% V
% Trp:
0
0
8
0
0
8
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _